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The main research focus of the Petrovič laboratory is
on global regulation of cellular homeostasis, with a specific
focus on lipid metabolism, with the aim to extend the obtained
knowledge to biomedical and biotechnological applications. We use yeast Saccharomyces cerevisiae, the most
suitable eukaryotic model organism for genome-scale studies, to investigate basic biological phenomena. The experimental
techniques used in the laboratory include high-throughput genetics for QTL
mapping (X-QTL), synthetic genetic array (SGA) analysis and synthetic dosage
lethality (SDL) analysis, high-content screening, chemogenomics,
high-throughput phenotyping and transcriptome analysis. We also develop
bioinformatics algorithms for the analysis of functional genomics data. |