Department of Biochemistry and Molecular Biology, J. Stefan Institute

in alphabetical order of the first authors (underlined are members of our department):

Gregor Anderluh, Jo"ze Punger"car, Borut "Strukelj, Peter Ma"cek, Franc Guben"sek (1995) The coding region of the equinatoxin II gene lacks introns. Croat. Chem. Acta 68 (3) 533-542 (S-518)

Jo"ze Brzin, Marjetka Kidri"c (1995) Proteinases and their inhibitors in plants: Role in normal growth and in response to various stress conditions. Biotechnol. Gen. Engng. Rev. 13, 421-467 (S-536)

Iztok Dolenc, Boris Turk, Galina Punger"ci"c, Anka Ritonja, Vito Turk (1995) Oligomeric structure and substrate induced inhibition of human cathepsin C. J. Biol. Chem. 270 (37) 21626-21631 (S-516)

Marko Dolinar, Darja Barli"c Maganja, Vito Turk (1995) Expression of full-length human procathepsin L cDNA in Escherichia coli and refolding of the expression product. Biol. Chem. Hoppe-Seyler 376, 385-388 (S-507)

Eva Ersdal-Badjou, Aiqin Lu, Xiaoming Peng, Veronique Picard, Pedram Zendehrouh, Boris Turk, Ingemar Bjork, Steven T. Olson, Susan C. Bock (1995) Elimination of glycosylation heterogeneity affecting heparin affinity of recombinant human antithrombin III by expression of a beta-like variant in baculovirus-infected insect cells. Biochem. J. 310, 323-330

Roman Hlodan, Roger H. Pain (1995) The folding and assembly pathway of tumour necrosis factor TNFalpha, a globular trimeric protein. Eur. J. Biochem. 231, 381-387 (S-511)

Roman Jerala, Gordon S. Rule (1995) A 3D 1H, 15N and 13C NOESY correlating experiment. J. Magn. Reson. 108, 294-298 (S-517)

Du"san Kordi"s, Franc Guben"sek (1995) Horizontal SINE transfer between vertebrate classes. Nature Genetics 10, 131-132 (S-509)

Janko Kos, Alojz "Smid, Marta Kra"sovec, Branka Svetic, Brigita Lenar"ci"c, Ivan Vrhovec, Janez "Skrk, Vito Turk (1995) Lysosomal proteases cathepsins D, B, H, L and their inhibitors stefins A and B in head and neck cancer. Biol. Chem. Hoppe-Seyler 376, 401-405 (S-510)

Igor Kri"zaj, E.G. Rowan, Franc Guben"sek (1995) Ammodytoxin A acceptor in bovine brain synaptic membranes. Toxicon 33 (4), 437-449 (S-506)

Robert Kuhelj, Marko Dolinar, Jo"ze Punger"car, Vito Turk (1995) The preparation of catalytically active human cathepsin B from its precursor expressed in Escherichia coli in the form of inclusion bodies. Eur. J. Biochem. 229, 533-539 (S-504)

Tamara T. Lah, Marguerite Hawley, Kenneth L. Rock, Alfred L. Goldberg (1995) Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages. FEBS Lett. 363, 85-89 (S-500)

Tamara T. Lah, Gloria Calaf, Endre Kalman, Balasahib G. Shinde, Jose Russo, David Jarosz, James Zabrecky, Robert Somers, Ierachimel Daskal (1995) Cathepsins D, B and L in breast carcinoma and in transformed human breast epithelial cells (HBEC). Biol. Chem. Hoppe-Seyler 376, 357-363 (S-508)

John R. Martin, C. Jeremy Craven, Roman Jerala, Louise Kroon-"Zitko, Eva "Zerovnik, Vito Turk, Jonathan P. Waltho (1995) The three-dimensional solution structure of human stefin A. J. Mol. Biol. 246, 331-343 (S-495)

Roger Pain (1995) Overview of protein folding. In: Current protocols in protein science 6.4.1-6.4.7. John Wiley & Sons (S-544)

Alenka Pari"s, Borut "Strukelj, Jo"ze Punger"car, Metka Renko, Iztok Dolenc, Vito Turk (1995) Molecular cloning and sequence analysis of human preprocathepsin C. FEBS Lett. 369, 326-330 (S-512)

J.Z. Pedersen, B. Lomonte, R. Massoud, Franc Guben"sek, J.M. Gutierrez, S. Rufini (1995) Autocatalytic acylation of phospholipase-like myotoxins. Biochemistry 34 (14) 4670-4675 (S-503)

Maja Ravnikar, Borut "Strukelj, Mateja Polj"sak-Prijatelj, Irena Mavri"c, Pika Me"sko, Jo"ze Punger"car, Igor Kregar (1995) Immunolocalization of aspartic proteinase inhibitors in potato shoots induced by jasmonic acid in vitro. Acta Pharm. 45, 139-145 (S-515)

Karl Ritsert, Robert Huber, Dusan Turk, Rudolf Ladenstein, Karen Schmidt-Baese, Adalbert Bacher (1995) Studies of the lumazine synthase/riboflavin synthase complex of Bacillus subtilis: Crystal structure analysis of reconstituted, icosahedral beta-subunit capsids with bound substrate analogue inhibitor at 2.4 A resolution. J. Mol. Biol. 253, 151-167 (S-523)

Veronika Stoka, Maria Nycander, Brigita Lenar"ci"c, Carlos Labriola, Juan Jose Cazzulo, Ingemar Bjork, Vito Turk (1995) Inhibition of cruzipain, the major cysteine proteinase of the protozoan parasite, Trypanosoma cruzi, by proteinase inhibitors of the cystatin superfamily. FEBS Lett. 370, 101-104 (S-514)

Borut "Strukelj, Jo"ze Punger"car, Gregor Kopitar, Metka Renko, Brigita Lenar"ci"c, Selma Berbi'c, Vito Turk (1995) Molecular cloning and identification of a novel porcine cathelin-like antibacterial peptide precursor. Biol. Chem. Hoppe-Seyler 376, 507-510 (S-513)

Borut "Strukelj, Maja Ravnikar, Pika Me"sko, Mateja Polj"sak-Prijatelj, Jo"ze Punger"car, Gregor Kopitar, Igor Kregar, Vito Turk (1995) Molecular cloning and immunocytochemical localization of jasmonic acid inducible cathepsin D inhibitors from potato. In: Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications (Kenji Takahashi, ed.), Plenum Press, New York, pp. 293-298 (S-520)

Boris Turk, Anka Ritonja, Ingemar Bjork, Veronika Stoka, Iztok Dolenc, Vito Turk (1995) Identification of bovine stefin A, a novel protein inhibitor of cysteine proteinases. FEBS Lett. 360, 101-105 (S-496)

Boris Turk, Joseph G. Bieth, Ingemar Bjork, Iztok Dolenc, Du"san Turk, Nina Cimerman, Janko Kos, Adrijana "Coli"c, Veronika Stoka, Vito Turk (1995) Regulation of the activity of lysosomal cysteine proteinases by pH-induced inactivation and/or endogenous protein inhibitors, cystatins. Biol. Chem. Hope-Seyler 376, 225-230 (S-502)

Boris Turk, Veronika Stoka, Ingemar Bjork, Christian Boudier, Gunnar Johansson, Iztok Dolenc, Adrijana "Coli'c, Joseph G. Bieth, Vito Turk (1995) High-affinity binding of two molecules of cysteine proteinases to low-molecular-weight kininogen. Protein Science 4, 1874-1880 (S-519)

Du"san Turk, Marjeta Podobnik, Tatjana Popovi"c, Nobuhiko Katunuma, Wolfram Bode, Robert Huber, Vito Turk (1995) Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors. Biochemistry 34 (14) 4791-4797 (S-501)

Vito Turk, Veronika Stoka, Boris Turk, Brigita Lenar"ci"c (1995) Properties, structure and interaction of lysosomal cysteine proteinases with their protein inhibitors cystatins. In: Expression of tissue proteinases and regulation of protein degradation as related to meat quality (A. Ouali, D.I. Deymer, F.J.M. Smulders, eds.) ECCEAMST, pp. 199-212 (S-522)

1996

Gregor Anderluh, Jo"ze Punger"car, Borut "Strukelj, Peter Ma"cek, Franc Guben"sek (1996) Cloning, sequencing, and expression of equinatoxin II. Biochem. Biophys. Res. Comm. 220, 437-442 (S-525)

Tadeja Bevec, Veronika Stoka, Galina Punger"ci"c, Iztok Dolenc, Vito Turk (1996) Major histocompatibility complex class II-associated p41 invariant chain fragment is a strong inhibitor of lysosomal cathepsin L. J. Exp. Med. 183, 1331-1338 (S-529)

Marjan Budihna, Primo"z Strojan, Lojze "Smid, Janez "Skrk, Ivan Vrhovec, Avgust "Zupevc, Zvonimir Rudolf, Miha "Zargi, Marta Kra"sovec, Branka Svetic, Nata"sa Kopitar-Jerala, Janko Kos (1996) Prognostic value of cathepsins B, H, L, D and their endogenous inhibitors stefins A and B in head and neck carcinoma. Biol. Chem. Hoppe-Seyler 377, 385-390 (S-539)

Nina Cimerman, Marinka Drobni"c Ko"sorok, Bruce D. Korant, Boris Turk, Vito Turk (1996) Characterization of cystatin C from bovine parotid glands: Cysteine proteinase inhibition and antiviral properties. Biol. Chem. Hoppe-Seyler 377, 19-23 (S-521)

Iztok Dolenc, Boris Turk, Janko Kos, Vito Turk (1996) Interaction of human cathepsin C with chicken cystatin. FEBS Lett. 392, 277-280 (S-541)

Roman Jerala, Paulo F.F. Almeida, Rodney L. Biltonen (1996) Simulation of the gel-fluid transition in a membrane composed of lipids with two connected acyl chains: Application of a dimer-move step. Biophys. J. 71, 609-615 (S-534)

Roman Jerala, Paulo F.F. Almeida, Qiang Ye, Rodney L. Biltonen, Gordon S. Rule (1996) ¹H, ¹⁵N and ¹³C resonance assignments and secondary structure of group II phospholipase A2 from Agkistrodon piscivorus piscivorus: Presence of an amino-terminal helix in solution. J. Biomolec. NMR 7, 107-120 (S-535)

Gregor Kopitar, Marko Dolinar, Borut "Strukelj, Jo"ze Punger"car, Vito Turk (1996) Folding and activation of human procathepsin S from inclusion bodies produced in Escherichia coli. Eur. J. Biochem. 236, 558-562 (S-524)

Du"san Kordi"s, Franc Guben"sek (1996) Ammodytoxin C gene helps to elucidate the irregular structure of Crotalinae group II phospholipase A₂ genes. Eur. J. Biochem. 240, 83-90 (S-540)

Janko Kos (1996) Lysosomal proteases and their inhibitors in malignant progression. In: Proceedings of the Croatian-Slovenian Meeting Molecular Oncology Today (Maja Osmak and Janez "Skrk, eds.), Croatian League against Cancer, Zagreb, pp. 89-96 (S-530/1)

Janko Kos, Borut "Stabuc, Marta Kra"sevec, Ana Schweiger, Branka Svetic, Nata"sa Kopitar-Jerala, Janja Ocvirk, Nina Cimerman, Zvonimir Rudolf, Ivan Vrhovec (1996) Lysosomal proteases cathepsins B, H, L and their inhibitors stefin A and cystatin C in sera of patients with metastatic melanoma. In: Proceedings of the Croatian-Slovenian Meeting Molecular Oncology Today (Maja Osmak and Janez "Skrk, eds.), Croatian League against Cancer, Zagreb, pp. 97-103 (S-530/2)

Janko Kos (1996) Cathepsins & their inhibitors - new factors for prognosis in cancer. Eur. Clin. Lab., June 1996 (S-538)

Igor Kri"zaj, Grazyna Faure, Franc Guben"sek, Cassian Bon (1996) Re-examination of crotoxin-membrane interactions. Toxicon 34, 1003-1009 (S-546)

Igor Kri"zaj, Avner Bdolah, Franc Guben"sek, Petra Ben"cina, Jo"ze Punger"car (1996) Protein and cDNA structures of an acidic phospholipase A₂, the enzymatic part of an unususal, two-component toxin from Vipera palestinae, Biochem. Biophys. Res. Comm. 227, 374-379 (S-547)

Tamara T. Lah, Gloria Calaf, Endre Kalman, Balasahib G. Shinde, Robert Somers, Sandino Estrada, Enrique Salero, Jose Russo, Ierachimel Daskal (1996) Cathepsins D, B, and L in transformed human breast epithelial cells. Breast Canc. Res. Treat. 39, 221-233 (S-537)

Panayotis Ledakis, William T. Tester, Nirit Rosenberg, David Romero-Fischmann, Ierachimel Daskal, Tamara T. Lah (1996) Cathepsins D, B, and L in malignant human lung tissue. Clinical Cancer Res. 2, 561-568 (S-551)

Brigita Lenar"ci"c, Igor Kri"zaj, Petra "Zunec, Vito Turk (1996) Differences in specificity for the interactions of stefins A, B and D with cysteine proteinases. FEBS Lett. 395, 113-118 (S-548)

Adrijana Leonardi, Boris Turk, Vito Turk (1996) Inhibition of bovine cathepsins L and S by stefins and cystatins. Biol. Chem. Hoppe-Seyler 377, 319-321 (S-528)

Djurdjica Novak Despot, Janko Kos, Gregor Ser"sa, Maja "Cema"zar, Bojan Mitrovi"c, Janez "Skrk, Franc Guben"sek (1996) Boronated monoclonal antibodies: A new tool in cancer treatment. In: Proceedings of the Croatian-Slovenian Meeting Molecular Oncology Today (Maja Osmak and Janez "Skrk, eds.), Croatian League against Cancer, Zagreb, pp. 175-178 (S-530/4)

Roger Pain (1996) Determining the CD spectrum of a protein. Current protocols in protein science 7.6.1-7.6.23. J. Wiley & Sons (S-545)

Tatjana Popovi"c, Vida Puizdar, Anka Ritonja, Jo"ze Brzin (1996) Simultaneous isolation of human kidney cathepsins B, H, L and C and their characterisation. J. Chromatogr. B 681, 251-262 (S-533)

Anka Ritonja, Theresa H.T. Coetzer, Robert N. Pike, Clive Dennison (1996) The amino acid sequences, structure comparisons and inhibition kinetics of sheep cathepsin L and sheep stefin B. Comp. Biochem. Physiol. 114B, 193-198 (S-542)

Paola Storici, Alessandro Tossi, Brigita Lenar"ci"c, Domenico Romeo (1996) Purification and structural characterization of bovine cathelicidins, precursors af antimicrobial peptides. Eur. J. Biochem. 238, 769-776 (S-532)

Primo"z Strojan, Marjan Budihna, Janez "Skrk, Lojze "Smid, Janko Kos, Ivan Vrhovec (1996) Cathepsins B, H, L, D and their endogenous inhibitors stefins A and B in head and neck carcinoma. In: Proceedings of the Croatian-Slovenian Meeting Molecular Oncology Today (Maja Osmak and Janez "Skrk, eds.), Croatian League against Cancer, Zagreb, pp. 105-111 (S-530/3)

Primo"z Strojan, Marjan Budihna, Lojze "Smid, Janez "Skrk, Janko Kos, Ivan Vrhovec, Miha "Zargi, Avgust "Zupevc, Zvonimir Rudolf (1996) The role of cathepsins and stefins as prognostic factors in patients with carcinoma in the head and neck region. Med. Razgl. 35 Suppl. 6, 139-144 (S-555)

Boris Turk, Veronika Stoka, Vito Turk, Gunnar Johansson, Juan Jose Cazzulo, Ingemar Bjork (1996) High-molecular-weight kininogen binds two molecules of cysteine proteinases with different rate constants. FEBS Lett. 391, 109-112 (S-531)

Du"san Turk, Marjeta Podobnik, Robert Kuhelj, Marko Dolinar, Vito Turk (1996) Crystal structures of human procathepsin B at 3.2 and 3.3 A resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide. FEBS Lett. 384, 211-214 (S-527)

Marc Vanhove, Xavier Raquet, Thimothy Palzkill, Roger H. Pain, Jean-Marie Frere (1996) The rate-limiting step in the folding of the cis-Pro167Thr mutant of TEM-1 beta-lactamase is the trans to cis isomerization of a non-prolinne peptide bond. Proteins: Struct. Funct. Genet. 25, 104-111 (S-543)

Alois Zajc, Maria Joao Romao, Boris Turk, Robert Huber (1996) Crystallographic and fluorescence studies of ligand binding to N-carbamoylsarcosine amidohydrolase from Arthrobacter sp. J. Mol. Biol. 263, 269-283 (S-549)

1997
 

Gregor Anderluh, Jo"ze Punger"car, Igor Kri"zaj, Borut "Strukelj, Franc Guben"sek, Peter Ma"cek (1997)
N-terminal truncation mutagenesis of equinatoxin II, a pore-forming protein from the sea anemone Actinia
equina. Protein Engineering 10, 751-755 (S-573)

Tadeja Bevec, Veronika Stoka, Galina Punger"ci"c, Juan Jose Cazzulo, Vito Turk (1997) A fragment of the major
histocompatibility complex class II - associated p41 invariant chain inhibits cruzipain, the major cysteine
proteinase from Trypanosoma cruzi. FEBS Lett. 401, 259-261 (S-559)

Juan Jose Cazzulo, Veronika Stoka, Vito Turk (1997) Cruzipain, the major cysteine proteinase from the
protozoan parasite Trypanosoma cruzi. Biol. Chem. 378, 1-10 (S-661)

Eileen Ebert, Bernd Werle, Britta Jülke, Natasa Kopitar-Jerala, Janko Kos, Tamara Lah, Magnus Abrahamson,
Eberhard Spiess, Werner Ebert (1997) Expression of cysteine protease inhibitors stefin A, stefin B, and cystatin
C in human lung tumor tissue. Adv. Exp. Med. Biol. 421, 259-265 (S-580)

Kristina Gruden, Borut "Strukelj, Maja Ravnikar, Mateja Polj"sak-Prijatelj, Irena Mavri"c, Jo"ze Brzin, Jo"ze
Punger"car, Igor Kregar (1997) Potato cysteine proteinase inhibitor gene family: molecular cloning,
characterisation and immunocytochemical localisation studies. Plant Mol. Biol. 34, 317-323 (S-569)

Franc Guben"sek, Du"san Kordi"s (1997) Venom phospholipase A2 genes and their molecular evolution. In:
Venom phospholipase A2 enzymes: Structure, function and mechanism (R.M. Kini, ed.), J. Wiley & Sons, pp.
73-95 (S-557)

Franc Guben"sek, Igor Kri"zaj, Jo"ze Punger"car (1997) Monomeric phospholipase A2 neurotoxins. In: Venom
phospholipase A2 enzymes: Structure, function and mechanism (R.M. Kini, ed.), J. Wiley & Sons, pp. 245-268
(S-558)

Hans-Heinrich Heidtmann, Ursula Salge, Magnus Abrahamson, Mojca Ben"cina, Lili Kastelic, Nata"sa
Kopitar-Jerala, Vito Turk, Tamara T. Lah (1997) Cathepsin B and cysteine proteinase inhibitors in human lung
cancer cell lines. Clin. Exp. Metastasis 15, 368-381 (S-572)

Du"san Kordi"s, Franc Guben"sek (1997) Bov-B long interspersed repreated DNA (LINE) sequences are present
in Vipera ammodytes phospholipase A2 genes and in genomes of Viperidae snakes. Eur. J. Biochem. 246,
772-779 (S-568)

Janko Kos, Borut Štabuc, Ana Schweiger, Marta Krašovec, Nina Cimerman, Nataša Kopitar-Jerala, Ivan
Vrhovec (1997) Cathepsins B, H, and L and their inhibitors stefin A and cystatin C in sera of melanoma patients.
Clinical Cancer research 3, 1815-1822 (S-575)

Samo Kreft, Maja Ravnikar, Pika Me"sko, Jo"ze Punger"car, Andrej Umek, Igor Kregar, Borut "Strukelj (1997)
Jasmonic acid inducible aspartic proteinase inhibitors from potato. Phytochem. 44, 1001-1006 (S-560)

Igor Kri"zaj, Grazyna Faure, Franc Guben"sek, Cassian Bon (1997) Neurotoxic phospholipases A2 ammodytoxin
and crotoxin bind to distinct high-affinity protein acceptors in Torpedo marmorata electric organ. Biochemistry
36, 2779-2787 (S-563)

Tamara T. Lah, Janko Kos, Andrej Blejec, Sne"zana Frkovi"c-Georgio, Rastko Golouh, Ivan Vrhovec, Vito Turk
(1997) The expression of lysosomal proteinases and their inhibitors in breast cancer: Possible relationship to
prognosis of the disease. Pathology Oncology Reseach 3, 89-99 (S-576)

Brigita Lenar"ci"c, Anka Ritonja, Borut "Strukelj, Boris Turk, Vito Turk (1997) Equistatin, a new inhibitor of
cysteine proteinases from Actinia equina, is structurally related to thyroglobulin type-1 domain J. Biol. Chem.
272, 13899-13903 (S-570)

Bojana Mozeti"c-Francky, Vladimir Coti"c, Anka Ritonja, Eva "Zerovnik, Andrej Francky (1997) High-yield
expression and purification of recombinant human macrophage migration inhibitory factor. Protein Express. Purif.
9, 115-124 (S-562)

Djurdica Novak Despot, Janko Kos, Gregor Ser"sa, Maja "Cema"zar, Janez "Skrk, Franc Guben"sek (1997)
Boronated CDI 315B monoclonal antibody and its potential use in boron neutron capture therapy. In: Advances in
neutron capture therapy. Vol. II, Chemistry and biology (B. Larsson, J. Crawford, R. Weinreich, eds.). Elsevier
Science B.V. pp. 516-518 (S-581)

Marjetka Podobnik, Robert Kuhelj, Vito Turk, Du"san Turk (1997) Crystal structure of the wild-type human
procathepsin B at 2.5 A resolution reveals the native active site of a papain-like cysteine protease zymogen. J.
Mol. Biol. 271, 774-788 (S-574)

Jo"ze Punger"car, Gregor Anderluh, Peter Ma"cek, Franc Guben"sek, Borut "Strukelj (1997) Sequence analysis
of the cDNA encoding the precursor of equinatoxin V, a newly discovered hemolysin from the sea anemone
Actinia equina. Biochim. Biophys. Acta 1341, 105-107 (S-578)

Ana Schweiger, Borut "Stabuc, Tatjana Popovi'c, Vito Turk, Janko Kos (1997) Enzyme-linked immunosorbent
assay for the detection of total cathepsin H in human tissue cytosols and sera. J. Immunol. Methods 201,
165-172 (S-564)

Lojze "Smid, Primo"z Strojan, Marjan Budihna, Janez "Skrk, Ivan Vrhovec, Miha "Zargi, Janko Kos (1997)
Prognostic value of cathepsins B, D and stefins A and B in laryngeal carcinoma. Eur. Arch. Othorinolaryngol. 254 Supl. 1, S150-S153 (S-556)

Boris Turk, Ingrid Brieditis, Susan C. Bock, Steven T. Olson, Ingemar Bjork (1997) The oligosaccharide side
chain on Asn-135 of alpha-antithrombin, absent in beta-antithrombin, decreases the heparin affinity of the
inhibitor by affecting the heparin-induced conformational change. Biochemistry 36, 6682-6691 (S-571)

Boris Turk, Vito Turk, Du"san Turk (1997) Structural and functional aspects of papain-like cysteine proteinases
and their protein inhibitors. Biol. Chem. 378, 141-150 (S-566)

Vito Turk, Marjetka Podobnik, Brigita Lenar"ci"c, Tadeja Bevec, Veronika Stoka, Boris Turk, Du"san Turk (1997)
New aspects of the regulation of activity of cysteine proteinases. In: Medical aspects of proteases and protease
inhibitors (N. Katanuma et al., eds.) IOS Press, pp. 3-14 (S-582)

Marc Vanhove, Gilliane Guillaume, Philippe Ledent, John H. Richards, Roger H. Pain, Jean-Marie Frere (1997)
Kinetic and thermodynamic consequences of the removal of the Cys-77 - Cys-123 disulphide bond for the folding
of TEM-1 beta-lactamase. Biochem. J. 321, 413-417 (S-554)

Bernd Werle, Britta Jülke, Tamara Lah, Janko Kos, Eberhard Spiess, Werner Ebert (1997) Cathepsin B and
cathepsin L: Prognostic factors in human lung cancer? In: Proteolysis in cell functions (Eds.: V.K. Hopsu-Havu et
al.), IOS Press, pp. 472-478 (S-579)

Petra Zrim"sek, Janko Kos, Franc Guben"sek (1997) The use of antibodies in determination of
pharmacologically active sites ion protein toxins. Vet. Nov. 23, 131-136 (S-565)

Eva "Zerovnik, Roman Jerala, Luise Kroon-"Zitko, Vito Turk, Karel Lohner (1997) Characterization of the
equilibrium intermediates in acid denaturation of human stefin B. Eur. J. Biochem. 245, 365-372 (S-567)

Eva "Zerovnik, Nina Cimerman, Janko Kos, Vito Turk, Karl Lohner (1997) Thermal denaturation of huamn
cystatin C and two of its variants; Comparison to chicken cystatin. Biol. Chem. 378, 1199-1203 (S-577)

1998
 

Gregor Anderluh, Ariana Barli"c, Igor Kri"zaj, Gianfranco Menestrina, Franc Guben"sek, Peter Ma"cek (1998)
Avidin-FITC topolgical studies with three cysteine mutants of equinatoxin II, a sea anemone pore-forming
protein. Biochem. Biophys. Res. Comm. 242, 187-190 (S-585)

Darja Barli"c Maganja, Marko Dolinar, Vito Turk (1998) The influence of Ala205 on the specificity of cathepsin L
produced by dextran sulfate assisted activation of the recombinant proenzyme. Biol. Chem. 379, 1449-1452
(S-611)

Jo"ze Brzin, Tatjana Popovi"c, Anka Ritonja, Vida Puizdar, Marjetka Kidri"c (1998) Related cystatin inhibitors
from leaf and from seed Phaseolus vulgaris L. Plant Science 138, 17-26 (S-614)

Bla"z Cigi'c, Igor Kri"zaj, Bogdan Kralj, Vito Turk, Roger H. Pain (1998) Stoichiometry and heterogeneity of the
pro-region chain in tetrameric human cathepsin C. Biochim. Biophys. Acta 1382, 143-150 (S-587)

Iztok Dolenc, Erika Seemüller, Wolfgang Baumeister (1998) Decelerated degradation of short peptides by the
20S proteasome. FEBS Lett. 434, 357-361 (S-605)

John A. Foekens, Janko Kos, Harry A. Peters, Marta Kra"sovec, Maxime P. Look, Nina Cimerman, Marion E.
Meijer-van Gelder, Sonja C. Henzen-Longmans, Wim L.J. van Putten, Jan G.M. Klijn (1998) Prognostic
significance of cathepsins B and L in primary breast cancer. J. Clin. Oncol. 16, 1013-1021 (S-590)

Kristina Gruden, Borut "Strukelj, Tatjana Popovi"c, Brigita Lenar"ci"c, Tadeja Bevec, Jo"ze Brzin, Igor Kregar,
Jana Herzog-Velikonja, Willem J. Stiekema, Dirk Bosch, Maarten A. Jongsma (1998) The cysteine protease
activity of Colorado potato beetle (Leptinotarsa decemlineata Say) guts, which is insensitive to potato protease
inhibitors, is inhibited by thyroglobulin type-1 domain inhibitors. Insect Biochem. Mol. Biol. 28, 549-560 (S-602)

Gregor Gun"car, Marjetka Podobnik, Jo"ze Punger"car, Borut "Strukelj, Vito Turk, Du"san Turk (1998) Crystal
structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chani C-terminal carboxyl
group defines cathepsin H aminopeptidase function. Structure 6, 51-61 (S-583)

Roman Jerala, Eva "Zerovnik, Jurka Kidri"c, Vito Turk (1998) pH-induced conformational transitions of the
propeptide of human cathepsin L. J. Biol. Chem. 273, 11498-11504 (S-595)

Du"san Kordi"s, Franc Guben"sek (1998) Unusual horizontal transfer of a long interspersed nuclear element
between distant vertebrate classes. Proc. Natl. Acad. Sci. USA 95, 10704-10709 (S-604)

Du"san Kordi"s, Franc Guben"sek (1998) The Bov-B LINEs found in Vipera ammodytes toxic PLA2 genes are
widespread in snake genomes. Toxicon 36, 1585-1590 (S-609)

Du"san Kordi"s, Avner Bdolah, Franc Guben"sek (1998) Positive Darwinian selection in Vipera palestinae
phospholipase A2 genes is unexpectedly limited to the third exon. Biochem. Biophys. Res. Comm. 251, 613-619
(S-610)

Janko Kos, Hans-Jorgen Nielsen, Marta Kra"sovec, Ib Jarle Christensen, Nina Cimerman, Ross W. Stephens,
Nils Brünner (1998) Prognostic values of cathepsin B abd carcinoembryonic antigen in sera of patients with
colorectal cancer. Clin. Cancer Res. 4, 1511-1516 (S-596)

Janko Kos, Tamara Lah (1998) Cysteine proteinases and their endogenous inhibitors: Target proteins for
prognosis, diagnosis and therapy in cancer (Review). Oncology Reports 5, 1349-1361 (S-607)

Janko Kos, Borut "Stabuc, Nina Cimerman, Nils Brünner (1998) Serum cystatin C, a new marker of glomerular
filtration rate, is increased during malignant progression. Clinical Chemistry 44, 2556-2557 (S-612)

Tamara T. Lah, Janko Kos (1998) Cysteine proteinases in cancer progression and their clinical relevance for
progression. Biol. Chem. 379, 125-130 (S-586)

Brigita Lenar"ci"c, Tadeja Bevec (1998) Thyropins - New structurally related proteinase inhibitors. Biol. Chem.
379, 105-111 (S-584)

Tatjana Popovi"c, Marjetka Kidri"c, Vida Puizdar, Jo"ze Brzin (1998) Purification and characterization of two
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Jo"ze Punger"car, Nata"sa Vu"cemilo, Grazyna  Faure, Cassian Bon, Hubertus M. Verheij, Franc Guben"sek,
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Boris Rogelj, Tatjana Popovi"c, Anka Ritonja, Borut Strukelj, Jo"ze Brzin (1998) Chelidocystatin, a novel
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Erika Seemüller, Istok Dolenc, Andrei Lupas (1998) Eukaryotic 20S proteasome. In: Barrett, A.J., Rawlings,
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Janez Sketelj, Neva "Crne-Finderle, Borut "Strukelj, Jo"ze V. Trontelj, Dirk Pette (1998) Acetylcholinesterase
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Veronika Stoka, James H. McKerrow, Juan Jose Cazzulo, Vito Turk (1998) Substrate inhibition of cruzipain is
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Boris Turk, Iztok Dolenc, Vito Turk (1998) Dipeptidyl-peptidase I. In: Barrett, A.J., Rawlings, N.D. & Woessner,
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Du"san Turk, Gregor Gun"car, Marjetka Podobnik, Boris Turk (1998) Revised definition of substrate binding
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Marc Vanhove, Anabelle Lejeune, Giliane Guillaume, Richard Virden, Roger H. Pain, Franz X. Schmid,
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M. Vanhove, A. Lejeune, R. H. Pain (1998) Beta-lactamases as models for protein-folding studies. Cell. Mol.
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Nata"sa Vu"cemilo, Alenka "Copi"c, Franc Guben"sek, Igor Kri"zaj (1998) Identification of a new high-affinity
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Kerry A. Wheeler, Alastair R. Hawkins, Roger Pain, Richard Virden (1998) The slow step of folding of Staphylococcus aureus PC1 beta-lactamase involves the collapse of a surface loop rate limited by the trans to cis isomerisation of a non-proline peptide bond. Proteins 33, 550-557 (S-616)

Eva "Zerovnik, Gregor Kopitar, Janko Kos, Vito Turk (1998) Refolding of recombinant sulphonated procathepsin
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Eva "Zerovnik, Roman Jerala, Louise Kroon-"Zitko, Vito Turk (1998) Stability and folding studies of two
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Eva "Zerovnik, Richard Virden, Roman Jerala, Vito Turk, Jonathan P. Waltho (1998) On the mechanism of
human stefin B folding: I. Comparison to homologous stefin A. Influence of pH and trifluoroethanol on the fast
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Eva "Zerovnik, Roman Jerala, Richard Virden, Louise Kroon "Zitko, Vito Turk, Jonathan P. Waltho (1998) On the mechanism of human stefin B folding: II. Folding from GuHCl unfolded, TFE denatured, acid denatured, and acid intermediate states. Proteins 32, 304-313 (S-601)