Department of Biochemistry and Molecular Biology, 
J. Stefan Institute


List of publications in 2003
in alphabetical order of the first authors (underlined are members of our department):


M.S. Cheon, S.H. Kim, V. Ovod, N. Kopitar Jerala, J.I. Morgan, Y. Hatefi, T. Ijun, T. Takenava, G. Lubec (2003) Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part III). Amino Acids 24, 127-134 (S-759)

Iztok Dolenc, Marko Mihelič
(2003) Purification and primary structure determination of human lysosomal dipeptidase. Biol. Chem. 384, 317-320 (S-752)

Katja Galeša, Roger Pain, Maarten A. Jongsma, Vito Turk, Brigita Lenarčič (2003) Structural characterization of thyroglobulin type-1 domains of equistatin. FEBS Lett. 539, 120-124 (S-755)

Kristina Gruden, Tatjana Popovič, Nina Cimerman, Igor Križaj, Borut Štrukelj (2003) Diverse enzymatic specificities of digestive proteases, 'intestains', enable Colorado potato beetle larvae to counteract the poptato defence mechanism. Biol. Chem. 384, 305-301 (S-754)

Saša Jenko, Iztok Dolenc, Gregor Gunčar, Andreja Doberšek, Marjeta Podobnik, Dušan Turk (2003) Crystal structure of stefin A in complex with cathepsin H: N-terminal residues of inhibitors can adapt to the active sites of endo- and exopeptidases. J. Mol. Biol. 326, 875-885 (S-753)

Klaus Kayser, Natalia Richter, Peter Hufnagl, Gian Gayser, Janko Kos, Bernd Werle (2003) Expression, proliferation activity and clinical significance of cathepsin B and cathepsin L in operated lung cancer. Anticancer Res. 23, 2767-2772 (S-773)

Pika Meško Brguljan, Vito Turk, Nina Cimerman, Jože Brzin, Igor Križaj, Tatjana Popovič (2003) Human brain cathepsin H as a neuropeptide and bradykinin metabolizing enzyme. Peptides 24, 1977-1984 (S-773a)

Irena Mlinaric-Rascan, Boris Turk (2003) B cell receptor-mediated nuclear fragmentation proceeds in WEHI 231 cells in the absence of detectable DEVDase and FRase activity. FEBS Lett. 553 (2003) 51-55 (S-775)

B. Oppert, T.D. Morgan, K. Hartzer, B. Lenarčič, K. Galeša, J. Brzin, V. Turk, K. Yoza, K. Ohtsubo, K.J. Kramer (2003) Effects of proteinase inhibitors on digestive proteinases and growth of the red flour beetle, Trifolium castaneum (Herbst) (Coleoptera: Tenebrionidae). Comp. Biochem. Physiol. C 134, 481-490 (S-758)

Marjetka Podobnik, Tanya F. Weitze, Mike O'Donnell, John Kuriyan (2003) Nucleotide-induced conformational changes in an isolated Escherichia coli DNA polymerase III clamp loader subunit. Structure 11, 253-263 (S-757)

Aleš Premzl, Valentina Zavašnik-Bergant, Vito Turk, Janko Kos
(2003) Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. Experim. Cell Res. 283, 206-214 (S-751)

Aleš Premzl, Janko Kos (2003) Cysteine and aspartic proteases cathepsins B and D determine the invasiveness of MCF10A neoT cells. Radiol. Oncol. 37(4), 241-8. (S-767)

Petra Prijatelj, Jernej Šribar, Gabriela Ivanovski, Igor Križaj, Franc Gubenšek, Jože Pungerčar (2003) Identification of a novel biniding site for calmodulin in ammodytoxin A, a neurotoxic group IIA phospholipase A2. Eur. J. Biochem. 270, 3018-3025 (S-761)

Jerica Rozman-Pungerčar, Nataša Kopitar-Jerala, Matthew Bogyo, Dušan Turk, Olga Vasiljeva, Ivica Štefe, Peter Vandenabeele, Dieter Brömme,  Vida Puizdar, Marko Fonović, Mojca Trstenjak-Prebanda, Iztok Dolenc, Vito Turk, Boris Turk (2003) Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 10, 881-888 (S-763)

Janez Ščančar, Radmila Milačič, Miha Benedik, Igor Križaj (2003) Total metal concentrations in serum of dialysis patients and fractionation of Cu, Rb, Al, Fe and Zn in spent continous ambulatory peritoneal dialysis fluids. Talanta 59, 355-364 (S-748)

Jernej Šribar, Alenka Čopič, Mateja Poljšak-Prijatelj, Jošt Kuret, Uroš Logonder, Franc Gubenšek, Igor Križaj (2003) R25 is an intracellular membrane receptor for a snake venom secretory phospholipase A2. FEBS Lett. 553, 309-314 (S-764)

Jernej Šribar, Nicholas E. Sherman, Petra Prijatelj, Grazyna Faure, Franc Gubenšek, Jay W. Fox, Alastair Aitken, Jože Pungerčar, Igor Križaj (2003) The neurotoxic phospholipase A2 associates, through a non-phosphorylated binding motif, with 14-3-3- protein [gamma] and [epsylon] isoforms. Biochem. Biophys. Res. Comm. 302, 691-696 (S-765)

Boris Turk, Hans Fritz (2003) Vito Turk - 30 years of research on cysteine proteases and their inhibitors (Editorial) (2003) Biol. Chem. 384, 833-836 (S-760)

Dušan Turk, Gregor Gunčar (2003) Lysosomal cysteine proteases (cathepsins): promising drug targets. Acta Cryst. D59, 203-213 (S-750)

Dušan Turk, Boris Turk, Vito Turk (2003) Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets? Biochem. Soc. Symp. 70, 15-30 (S-765)

Olga Vasiljeva, Marko Dolinar, Vito Turk, Boris Turk (2003) Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry 42, 13522-13528 (S-772)

Vera Župunski, Dušan Kordiš, Franc Gubenšek (2003) Adaptive evolution in the snake venom Kunitz/BPTI protein family. FEBS Lett. 547, 131-136 (S-762)


List of publications in 2004
in alphabetical order of the first authors (underlined are members of our department):


Dieter Brömme, Ferez S. Nallaseth, Boris Turk (2004) Production and activation of recombinant papain-like cysteine proteases. Methods 32, 199-206 (S-774)

Mateja Cegnar, Aleš Premzl, Valentina Zavašnik-Bergant, Julijana Kristl, Janko Kos (2004) Poly(lactide-co-glycolide) nanoparticles as carrier system for delivering cysteine protease inhibitor cystatin into tumor cells. Exper. Cell Res. 301, 223-231 (S-789)

Tina Cirman, Kristina Orešić, Gabriela Droga Mazovec, Vito Turk, John C. Reed, Richard M. Myers, Guy S. Salvesen, Boris Turk (2004) Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J. Biol. Chem. 279, 3578-3587 (S-768)

Tamara Čimbora-Zovko, Sergeja Bombek, Janez Košmrlj, Lidija Kovačić, Slovenko Polanc, Ana Katalinić, Maja Osmak (2004) Development of potential anti-cancer agents: Diazenes and derivatives. Drug Devel. Res. 61, 95-100 (S-793)

Saša Čučnik, Igor Križaj, Blaž Rozman, Tanja Kveder, Borut Božič (2004) Concomitant isolation of protein C inhibitor and unnicked [beta]2-glycoprotein I. Clin. Chem. Lab. Med. 42 (2), 171-174 (S-771)

Tadej Čepeljnik, Igor Križaj, Romana Marinšek-Logar (2004) Isolation and characterization of the Pseudobutyrivibrio xylanivorans Mz5T xylanase XynT - the first family 11 endoxylanase from rumen Butyrivibrio-related bacteria. Enz. Microb. Technol. 34, 219-227 (S-769)

S. Čučnik, T. Kveder, I. Križaj, B. Rozman, B. Božič (2004) High avidity anti-beta2-glycoprotein I antibodies in patients with antiphospholipid syndrome. Ann. Rheum. Dis. 63, 1478-1482 (S-792)

Ndeye Ndack Diop, Marjetka Kidrič, Anne Repellin, Monique Gareil, Agnes d'Arcy-Lameta, Ahn Thu Pham Thi, Yasmine Zuily-Fodil (2004) A multicystatin is induced by drought-stress in cowpea (Vigna unculata (L.) Walp.) leaves. FEBS Lett. 577, 545-550 (S-788)

Marko Fonović, Dieter Brömme, Vito Turk, Boris Turk (2004) Human cathepsin F: expression in baculovirus system, characterization and inhibition by protein inhibitors. Biol. Chem. 385, 505-509 (S-783)

Katja Galeša, Richard M. Thomas, Marjetka Kidrič, Roger H. Pain (2004) Clitocypin, a new cysteine proteinase inhibitor, is monomeric: impact on the mechanism of folding. Biochem. Biophy.s Res. Comm. 324, 576-578 (S-786)

Benjamin Gorinšek, Franc Gubenšek, Dušan Kordiš (2004) Evolutionary genomics of Chromoviruses in Eukaryotes. Mol. Biol. Evol. 21 (5), 781-798 (S-787)

Bara Hieng
, Kristina Ugrinović, Jelka Šuštar-Vozlič, Marjetka Kidrič (2004) Different classes of proteases are involved in the response to drought of Phaseolus vulgaris L. cultivars differing in sensitivity. J. Plant Physiol. 161, 519-530 (S-781)

Gabriela Ivanovski, Toni Petan, Igor Križaj, Michael H. Gelb, Franc Gubenšek, Jože Pungerčar (2004) Basic amino acid residues in the bata-structure region contribute, but not critically, to presynaptic neurotoxicity of ammodytoxin A. Biochim. Biophys. Acta 1702, 217-225 (S-784)

Saša Jenko, Miha Škarabot, Manca Kenig, Gregor Gunčar, Igor Muševič, Dušan Turk, Eva Žerovnik (2004) Different propensity to form amyloid fibrils by two homologous proteins - human stefins A and B: Searching for explanation. Proteins 55, 417-425. (S-776)

Manca Kenig, Selma Berbić, Aida Kriještorac, Louise Kroon-Žitko, Magda Tušek, Maruša Pompe-Novak, Eva Žerovnik (2004) Differences in aggregation properties of three site-specific mutants of recombinant human stefin B. Protein Sci. 13, 63-70 (S-770)

Blaž Kralj, Janez Ščančar, Igor Križaj, Miha Benedik, Peter Bukovec, Radmila Milačič (2004) Determination of high molecular mass Al species in serum and spent CAPD fluids of dialysis patients combining SEC and anion-exchange FPLC with ETAAS detection. J. Anal. At. Spectrom. 19, 101-106 (S-766)

Uroš Petrovič, Jernej Šribar, Alenka Pariš, Marjan Rupnik, Mojca Kržan, Nina Vardjan, Franc Gubenšek, Robert Zorec, Igor Križaj (2004) Ammodytoxin, a neurotoxic secreted phospholipase A2, can act in the cytosol of the nerve cell. Biochem. Biophys. Res. Comm. 324, 981-985 (S-782)

Alejandro Rabossi, Veronika Stoka, Vida Puizdar, Vito Turk, Luis A. Quesada-Allué (2004) Novel aspartyl proteinase associated to fat body histolysis during Ceratitis capitata early metamorphosis. Arch. Insect Biochem. Physiol. 57, 51-67 (S-790)

Andrea Rossi, Quinn Deveraux, Boris Turk, Andrej Sali (2004) Comprehensive search for cysteine cathepsins in the human genome. Biol. Chem. 385, 363-372 (S-777)

L. Sacchi, R. Bellazzi, C. Larizza, P. Magni, T. Curk, U. Petrovic, B. Zupan (2004) Clustering gene expression data with temporal abstractions. In: MEDINFO 2004, M. Fieschi et al. (eds.), Amsterdam: IOS Press, pp. 798-802 (S-791)

Igor Štern, Norbert Schaschke, Luis Moroder, Dušan Turk (2004) Crystal structure of NS-134 in complex with bovine cathepsin B: a two-headed epoxysuccinyl inhibitor extends along the entire active-site cleft. Biochem. J. 381, 511-517 (S-780)

Boris Turk, Dusan Turk, Iztok Dolenc, Vito Turk (2004) Dipeptidyl-peptidase I. In: Handbook of Proteolytic Enzymes, 2nd Edn. Elsevier Ltd. pp. 192-1196 (S-785)

Vito Turk, Janko Kos, Boris Turk (2004) Cysteine cathepsins (proteases) - On the main stage of cancer? Cancer Cell 5 (5), 409-420 (S-778)

Valentina Zavašnik-Bergant, Ana Schweiger, Tadeja Bevec, Rastko Golouh, Vito Turk, Janko Kos (2004) Inhibitory p41 isoform of invariant chain and its potential target enzymes cathepsins L and H in distinct populations of macrophages in human lymph nodes. Immunology 112, 378-385 (S-779)



Last updated: September 12, 2006 (last reprint S-793).


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